diacylglycerol

diacylglycerol
Glycerol substituted on the 1 and 2 hydroxyl groups with long chain fatty acyl residues. DAG is a normal intermediate in the biosynthesis of phosphatidyl phospholipids and is released from them by phospholipase C activity. DAG from phosphatidyl inositol polyphosphates is important in signal transduction. Elevated levels of DAG in membranes activate protein kinase C by stabilizing its catalytically active complex with membrane-bound phosphatidyl serine and calcium.

Dictionary of molecular biology. 2004.

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  • diacylglycerol kinase — di·ac·yl·glyc·er·ol ki·nase (di a″səl glisґər ol kiґnās) [EC 2.7.1.107] an enzyme of the transferase class that catalyzes the phosphorylation of a diacylglycerol to form a phosphatidate, using ATP as a phosphate donor. Called …   Medical dictionary

  • Diacylglycerol — …   Википедия

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